SWEENEY LAB
SWEENEY LAB
SWEENEY LAB
Lab Publications
Lab Publications
Elevated Activity of the Mesolimbic Dopamine System Promotes Feeding During Pregnancy in Mice. T Pattnaik, B Wang, & P Sweeney (2026). Molecular Metabolism.
Reduced Melanocortin Tone Mediates Increased Feeding During Pregnancy in Mice. IC Possa-Paranhos, K Catalbas, S Congdon, T Pattnaik, C Nelson, D Cho, & P Sweeney (2025). BioRxiv (preprint).
Medial Hypothalamic MC3R Signalling Regulates Energy Rheostasis in Adult Mice. IC Possa-Paranhos, J Butts, E Pyszka, C Nelson, S Congdon, D Cho, & P Sweeney (2025). Journal of Physiology.
Hypothalamic AgRP Neurons Regulate the Hyperphagia of Lactation. K Catalbas, T Pattnaik, S Congdon, C Nelson, LC Villano, & P Sweeney (2024). Molecular Metabolism.
A Neural Pathway Integrating Stress and Feeding. J Butts & P Sweeney (2024). Neuropsychopharmacology.
Paraventricular Thalamic MC3R Circuits Link Energy Homeostasis with Anxiety-Related Behavior. D Cho, K O'Berry, IC Possa-Paranhos, J Butts, N Palanikumar, & P Sweeney (2023). Journal of Neuroscience.
Establishment of Restraint Stress-Induced Anorexia and Social Isolation-Induced Anorexia Mouse Models. IC Possa-Paranhos, K Catalbas, J Butts, K O'Berry, & P Sweeney (2023). Bio-Protocol.
Elevated Activity of the Mesolimbic Dopamine System Promotes Feeding During Pregnancy in Mice. T Pattnaik, B Wang, & P Sweeney (2026). Molecular Metabolism.
Reduced Melanocortin Tone Mediates Increased Feeding During Pregnancy in Mice. IC Possa-Paranhos, K Catalbas, S Congdon, T Pattnaik, C Nelson, D Cho, & P Sweeney (2025). BioRxiv (preprint).
Medial Hypothalamic MC3R Signalling Regulates Energy Rheostasis in Adult Mice. IC Possa-Paranhos, J Butts, E Pyszka, C Nelson, S Congdon, D Cho, & P Sweeney (2025). Journal of Physiology.
Hypothalamic AgRP Neurons Regulate the Hyperphagia of Lactation. K Catalbas, T Pattnaik, S Congdon, C Nelson, LC Villano, & P Sweeney (2024). Molecular Metabolism.
A Neural Pathway Integrating Stress and Feeding. J Butts & P Sweeney (2024). Neuropsychopharmacology.
Paraventricular Thalamic MC3R Circuits Link Energy Homeostasis with Anxiety-Related Behavior. D Cho, K O'Berry, IC Possa-Paranhos, J Butts, N Palanikumar, & P Sweeney (2023). Journal of Neuroscience.
Establishment of Restraint Stress-Induced Anorexia and Social Isolation-Induced Anorexia Mouse Models. IC Possa-Paranhos, K Catalbas, J Butts, K O'Berry, & P Sweeney (2023). Bio-Protocol.
PI Publications
PI Publications
Subthreshold Activation of the Melanocortin System Causes Generalized Sensitization to Anorectic Agents in Mice. NS Dahir, Y Gui, Y Wu, P Sweeney, AAJ Rouault, SY Williams, LE Gimenez, TK Sawyer, ST Joy, AK Mapp, & RD Cone (2024). Journal of Clinical Investigation.
28 Melanocortin 3 Receptor in Neural Circuits Linking Metabolic State with Reproduction and Growth. MN Bedenbaugh, S Sweet, H Mendoza-Romero, S Brener, S Hawkins, G Yu, J Zimmerman, P Sweeney, RD Cone, & RB Simerly (2023). Journal of Animal Science.
Melanocortin-3 Receptor Expression in AgRP Neurons is Required for Normal Activation of the Neurons in Response to Energy Deficiency. Y Gui, NS Dahir, Y Wu, G Downing, P Sweeney, & RD Cone (2023). Cell Reports.
Targeting the Central Melanocortin System for the Treatment of Metabolic Disorders. P Sweeney, LE Gimenez, CC Hernandez, & RD Cone (2023). Nature Reviews Endocrinology.
MC3R Links Nutritional State to Childhood Growth and the Timing of Puberty. BYH Lam, A Williamson, S Finer, FR Day, JA Tadross, A Goncalves Sorares, K Wade, P Sweeney, MN Bedenbaugh, DT Porter, A Melvin, KLJ Ellacott, … C Langenberg, JR Perry, GS Yeo, & S O’Rahilly (2021). Nature.
The Melanocortin 3 Receptor is a Pharmacological Target for the Regulation of Anorexia. P Sweeney, MN Bedenbaugh, J Maldonado, P Pan, K Fowler, SY Williams, LE Gimenez, M Ghamari-Langroudi, G Downing, Y Gui, CK Hadley, ST Joy, AK Mapp, RB Simerly, & RD Cone (2021). Science Translational Medicine.
Network Dynamics of Hypothalamic Feeding Neurons. P Sweeney, C Chen, I Rajapakse, & RD Cone (2021). Proceedings of the National Academy of Sciences.
An Excitatory Hypothalamus to Paraventricular Thalamus (PVT) Circuit that Suppresses Food Intake. J Zhang, D Chen, P Sweeney, & Y Yang (2020). Nature Communications.
Regulation of Energy Rheostasis by the Melanocortin-3 Receptor. M Ghamari-Langroudi, I Cakir, RN Lippert, P Sweeney, MJ Litt, KLJ Ellacott, & RD Cone (2018). Science Advances.
Appetite Suppressive Role of Medial Septal Area Glutamatergic Neurons. P Sweeney, C Li, & Y Yang (2017). Proceedings of the National Academy of Sciences.
HFD-Induced Energy States-Dependent Bidirectional Control of Anxiety Levels in Mice. P Sweeney, K O’Hara, Z Xu, & Y Yang (2017). International Journal of Obessity.
Neural Circuit Mechanisms Underlying Emotional Regulation of Homeostatic Feeding. P Sweeney & Y Yang (2017). Trends in Endocrinology & Metabolism.
Activation of Hypothalamic Astrocytes Suppresses Feeding without Altering Emotional States. P Sweeney, Y Qi, Z Xu, & Y Yang (2016). Glia.
An Inhibitory Septum to Lateral Hypothalamus Circuit that Suppresses Feeding. P Sweeney & Y Yang (2016). Journal of Neuroscience.
Caffeine Increases Food Intake While Reducing Anxiety-Related Behaviors. P Sweeney, R Levack, J Watters, Z Xu, & Y Yang (2016). Appetite.
An Excitatory Ventral Hippocampus to Lateral septum Circuit that Suppresses Feeding. P Sweeney & Y Yang (2015). Nature Communications.
Long-term Behavioral Consequences of Stress Exposure in Adolescent versus Young Adult Rats. ML Saul, D Tylee, KT Becoats, BG Guerrero, P Sweeney, DL Helmreich, JL Fudge (2012). Behavioral Brain Research.
Subthreshold Activation of the Melanocortin System Causes Generalized Sensitization to Anorectic Agents in Mice. NS Dahir, Y Gui, Y Wu, P Sweeney, AAJ Rouault, SY Williams, LE Gimenez, TK Sawyer, ST Joy, AK Mapp, & RD Cone (2024). Journal of Clinical Investigation.
28 Melanocortin 3 Receptor in Neural Circuits Linking Metabolic State with Reproduction and Growth. MN Bedenbaugh, S Sweet, H Mendoza-Romero, S Brener, S Hawkins, G Yu, J Zimmerman, P Sweeney, RD Cone, & RB Simerly (2023). Journal of Animal Science.
Melanocortin-3 Receptor Expression in AgRP Neurons is Required for Normal Activation of the Neurons in Response to Energy Deficiency. Y Gui, NS Dahir, Y Wu, G Downing, P Sweeney, & RD Cone (2023). Cell Reports.
Targeting the Central Melanocortin System for the Treatment of Metabolic Disorders. P Sweeney, LE Gimenez, CC Hernandez, & RD Cone (2023). Nature Reviews Endocrinology.
MC3R Links Nutritional State to Childhood Growth and the Timing of Puberty. BYH Lam, A Williamson, S Finer, FR Day, JA Tadross, A Goncalves Sorares, K Wade, P Sweeney, MN Bedenbaugh, DT Porter, A Melvin, KLJ Ellacott, … C Langenberg, JR Perry, GS Yeo, & S O’Rahilly (2021). Nature.
The Melanocortin 3 Receptor is a Pharmacological Target for the Regulation of Anorexia. P Sweeney, MN Bedenbaugh, J Maldonado, P Pan, K Fowler, SY Williams, LE Gimenez, M Ghamari-Langroudi, G Downing, Y Gui, CK Hadley, ST Joy, AK Mapp, RB Simerly, & RD Cone (2021). Science Translational Medicine.
Network Dynamics of Hypothalamic Feeding Neurons. P Sweeney, C Chen, I Rajapakse, & RD Cone (2021). Proceedings of the National Academy of Sciences.
An Excitatory Hypothalamus to Paraventricular Thalamus (PVT) Circuit that Suppresses Food Intake. J Zhang, D Chen, P Sweeney, & Y Yang (2020). Nature Communications.
Regulation of Energy Rheostasis by the Melanocortin-3 Receptor. M Ghamari-Langroudi, I Cakir, RN Lippert, P Sweeney, MJ Litt, KLJ Ellacott, & RD Cone (2018). Science Advances.
Appetite Suppressive Role of Medial Septal Area Glutamatergic Neurons. P Sweeney, C Li, & Y Yang (2017). Proceedings of the National Academy of Sciences.
HFD-Induced Energy States-Dependent Bidirectional Control of Anxiety Levels in Mice. P Sweeney, K O’Hara, Z Xu, & Y Yang (2017). International Journal of Obessity.
Neural Circuit Mechanisms Underlying Emotional Regulation of Homeostatic Feeding. P Sweeney & Y Yang (2017). Trends in Endocrinology & Metabolism.
Activation of Hypothalamic Astrocytes Suppresses Feeding without Altering Emotional States. P Sweeney, Y Qi, Z Xu, & Y Yang (2016). Glia.
An Inhibitory Septum to Lateral Hypothalamus Circuit that Suppresses Feeding. P Sweeney & Y Yang (2016). Journal of Neuroscience.
Caffeine Increases Food Intake While Reducing Anxiety-Related Behaviors. P Sweeney, R Levack, J Watters, Z Xu, & Y Yang (2016). Appetite.
An Excitatory Ventral Hippocampus to Lateral septum Circuit that Suppresses Feeding. P Sweeney & Y Yang (2015). Nature Communications.
Long-term Behavioral Consequences of Stress Exposure in Adolescent versus Young Adult Rats. ML Saul, D Tylee, KT Becoats, BG Guerrero, P Sweeney, DL Helmreich, JL Fudge (2012). Behavioral Brain Research.